v3.19.3

Note 1 - Organization and Basis of Presentation (Details Textual) |  |  | 1 Months Ended |  |  |
--- | --- | --- | --- | --- | --- | ---
May 31, 2019 USD ($) | May 03, 2019 | May 31, 2019 USD ($) | Apr. 30, 2019 USD ($) | Jun. 30, 2019 USD ($) | Dec. 31, 2018 USD ($) | Dec. 31, 2017 USD ($)
Cash and Cash Equivalents, at Carrying Value, Ending Balance |  |  |  |  | $ 24,000 | $ 1,887,000 | $ 4,301,000
Loans Payable, Total |  |  |  |  |  | 4,200,000 |
Retained Earnings (Accumulated Deficit), Ending Balance |  |  |  |  | (44,417,000) | $ (37,279,000) | $ (31,294,000)
Majority Investors [Member] |  |  |  |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage |  |  |  |  |  | 8.00% |
Majority Investors [Member] | First Note to Fund the Company's Operations [Member] |  |  |  |  |  |  |
Proceeds from Notes Payable, Total |  |  |  | $ 2,000,000 |  |  |
Majority Investors [Member] | Second Note to Fund the Company's Operations [Member] |  |  |  |  |  |  |
Proceeds from Notes Payable, Total | $ 500,000 |  | $ 500,000 |  |  |  |
Majority Investors [Member] | Notes to Fund the Company's Operations [Member] |  |  |  |  |  |  |
Debt Instrument, Interest Rate, Stated Percentage | 8.00% |  | 8.00% |  |  |  |
Convertible Debt [Member] |  |  |  |  |  |  |
Notes Payable, Total |  |  |  |  | 5,600,000 | $ 4,600,000 |
Oxford Finance, LLC [Member] |  |  |  |  |  |  |
Loans Payable, Total |  |  |  |  | $ 3,000,000 |  |
Reverse Stock Split From [Member] | Alliqua Biomedical, Inc. [Member] |  |  |  |  |  |  |
Stockholders' Equity Note, Stock Split, Conversion Ratio |  | 6 |  |  |  |  |
Alliqua Biomedical, Inc. [Member] |  |  |  |  |  |  |
Business Acquisition, Exchange Ratio |  | 0.0359 |  |  |  |  |

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