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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2024 | Mar. 31, 2023
Operating activities |  |
Net loss | $ (30,696) | $ (26,665)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation expense | 3,345 | 3,353
Non-cash interest expense on liability related to sales of future royalties and milestones, net of issuance costs accretion | 1,982 |
Depreciation and amortization | 42 | 58
Noncash lease expense | 269 | 375
Accretion of available-for-sale marketable securities, net | (510) | (94)
Changes in operating assets and liabilities: |  |
Accounts receivable, net - related party | 1,047 | (2,806)
Inventory, net | 80 | (1,132)
Other receivables | 49 | 1
Prepaid expenses | 2,364 | (928)
Accounts payable and accrued expenses | (10,151) | (6,318)
Operating lease liability |  | (462)
Reimbursement of lease incentive | 1,726 |
Net cash used in operating activities | (30,453) | (34,618)
Investing activities |  |
Proceeds from maturities of available-for-sale marketable securities | 59,000 | 29,500
Proceeds from redemptions of available-for-sale marketable securities, at par |  | 4,000
Purchases of available-for-sale marketable securities | (32,213) | (15,792)
Purchases of property and equipment | (836) |
Net cash provided by investing activities | 25,951 | 17,708
Financing activities |  |
Payments to royalty purchase and sale agreement | (685) |
Proceeds from the exercise of stock options |  | 560
Net cash (used in) provided by financing activities | (685) | 560
Net decrease in cash, cash equivalents and restricted cash | (5,187) | (16,350)
Cash, cash equivalents and restricted cash at beginning of period | 53,683 | 64,149
Cash, cash equivalents and restricted cash at end of period | 48,496 | $ 47,799
Noncash investing and financing activities |  |
Accrual for leasehold improvements | $ 211 |

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