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Income Taxes - Additional Information (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Income Taxes |  |  |
Company's effective tax rate | 0.56% | 0.00% | 0.00%
Percentage of eligible annual research and development credit for cash | 65.00% | 65.00% | 65.00%
Benefit from income taxes | $ (398) | $ 0 | $ 0
Valuation allowance on the deferred tax asset | 100.00% | 100.00% |
Change in valuation allowance | $ 7,865 | $ 31,977 |
Unrecognized tax benefits, related interest and penalties | $ 0 | $ 0 | $ 0
Tax examinations, description | tax years 2006 through 2024 remain open to U.S. federal and state tax examinations. |  |
Income taxes using U.S. federal statutory rate | 21.00% | 21.00% | 21.00%
Federal [Member] |  |  |
Income Taxes |  |  |
Net operating loss carryforwards | $ 475,440 |  |
Federal [Member] | Earliest Tax Year [Member] |  |  |
Income Taxes |  |  |
Tax loss carryforwards expiration year | 2026 |  |
Federal [Member] | R&D Tax Credit Carryforwards [Member] |  |  |
Income Taxes |  |  |
Tax credit carryforwards | $ 28,557 |  |
Federal [Member] | R&D Tax Credit Carryforwards [Member] | Earliest Tax Year [Member] |  |  |
Income Taxes |  |  |
Tax credit expiration year | 2025 |  |
State and Local [Member] |  |  |
Income Taxes |  |  |
Net operating loss carryforwards | $ 403,138 |  |
State and Local [Member] | Earliest Tax Year [Member] |  |  |
Income Taxes |  |  |
Tax loss carryforwards expiration year | 2027 |  |
State and Local [Member] | R&D Tax Credit Carryforwards [Member] |  |  |
Income Taxes |  |  |
Tax credit carryforwards | $ 4,379 |  |

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