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Revenue Recognition - Disaggregation of Revenue (Detail) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | $ 7,137 | $ 20,968 | $ 41,867
Collaborative revenue |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 2,086 | 12,936 | 16,572
Collaborative revenue | Maruishi Agreement [Member] |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 0 | 539 | 0
Collaborative revenue | Affiliated Entity [Member] | CSL Vifor Profit Sharing |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 2,086 | 12,397 | 16,572
Commercial supply revenue |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 640 | 5,843 | 10,223
Commercial supply revenue | Affiliated Entity [Member] | CSL Vifor |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 640 | 5,843 | 10,223
License and milestone fees |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue |  | 910 | 15,000
License and milestone fees | Maruishi Agreement [Member] |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 0 | 910 | 0
License and milestone fees | Affiliated Entity [Member] | CSL Vifor |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue |  |  | 15,000
License and milestone fees | Affiliated Entity [Member] | CSL Vifor |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue |  |  | 15,000
Royalty revenue |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue |  | 415 | 72
Royalty revenue | Affiliated Entity [Member] | CSL Vifor Kapruvia [Member] |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue |  | 415 | 72
Clinical compound revenue |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 84 | 165 |
Clinical compound revenue | Maruishi Agreement [Member] |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 84 | 165 | $ 0
Other revenue (non-cash) |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 4,327 | 699 |
Other revenue (non-cash) | Maruishi Agreement [Member] |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | 2,835 | 415 |
Other revenue (non-cash) | Affiliated Entity [Member] | CSL Vifor Kapruvia [Member] |  |  |
Disaggregation of Revenue [Line Items] |  |  |
Total revenue | $ 1,492 | $ 284 |

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