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Accounts Payable and Accrued Expenses - Schedule of Accounts Payable and Accrued Expenses (Detail) - USD ($) $ in Thousands | Dec. 31, 2024 | Dec. 31, 2023
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Accounts Payable and Accrued Expenses |  |
Accounts payable | $ 1,434 | $ 11,583
Accrued research projects | 64 | 4,343
Accrued compensation and benefits | 565 | 6,519
Accrued professional fees and other | 1,909 | 3,147
Total | $ 3,972 | $ 25,592

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