<SEC-DOCUMENT>0002049793-25-000001.txt : 20250422
<SEC-HEADER>0002049793-25-000001.hdr.sgml : 20250422
<ACCEPTANCE-DATETIME>20250422142613
ACCESSION NUMBER:		0002049793-25-000001
CONFORMED SUBMISSION TYPE:	SCHEDULE 13G
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20250422
DATE AS OF CHANGE:		20250422

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Tvardi Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001346830
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-87880
		FILM NUMBER:		25857103

	BUSINESS ADDRESS:	
		STREET 1:		3 SUGAR CREEK CTR. BLVD.
		STREET 2:		STE 525
		CITY:			SUGAR LAND
		STATE:			TX
		ZIP:			77478
		BUSINESS PHONE:		(713) 489-8654

	MAIL ADDRESS:	
		STREET 1:		3 SUGAR CREEK CTR. BLVD.
		STREET 2:		STE 525
		CITY:			SUGAR LAND
		STATE:			TX
		ZIP:			77478

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cara Therapeutics, Inc.
		DATE OF NAME CHANGE:	20100721

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cara Therapeutics Inc
		DATE OF NAME CHANGE:	20051213

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Solas Tvardi Sidecar LLC
		CENTRAL INDEX KEY:			0002049793
		ORGANIZATION NAME:           	
		EIN:				332012855
		STATE OF INCORPORATION:			TN
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SCHEDULE 13G

	BUSINESS ADDRESS:	
		STREET 1:		412 GEORGIA AVE
		STREET 2:		SUITE 201
		CITY:			CHATTANOOGA
		STATE:			TN
		ZIP:			37403
		BUSINESS PHONE:		423-234-3460

	MAIL ADDRESS:	
		STREET 1:		412 GEORGIA AVE
		STREET 2:		SUITE 201
		CITY:			CHATTANOOGA
		STATE:			TN
		ZIP:			37403
</SEC-HEADER>
<DOCUMENT>
<TYPE>SCHEDULE 13G
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
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  <headerData>
    <submissionType>SCHEDULE 13G</submissionType>
    <filerInfo>
      <filer>
        <filerCredentials>
          <cik>0002049793</cik>
          <ccc>XXXXXXXX</ccc>
        </filerCredentials>
      </filer>
      <liveTestFlag>LIVE</liveTestFlag>



    </filerInfo>
  </headerData>
  <formData>
    <coverPageHeader>
      <securitiesClassTitle>Common Stock of Tvardi Therapeutics, Inc.</securitiesClassTitle>
      <eventDateRequiresFilingThisStatement>04/15/2025</eventDateRequiresFilingThisStatement>
      <issuerInfo>
        <issuerCik>0001346830</issuerCik>
        <issuerName>Tvardi Therapeutics, Inc.</issuerName>
        <issuerCusip>140755208</issuerCusip>
        <issuerPrincipalExecutiveOfficeAddress>
          <com:street1>3 SUGAR CREEK CTR. BLVD.</com:street1>
          <com:street2>STE 525</com:street2>
          <com:city>SUGAR LAND</com:city>
          <com:stateOrCountry>TX</com:stateOrCountry>
          <com:zipCode>77478</com:zipCode>
        </issuerPrincipalExecutiveOfficeAddress>
      </issuerInfo>
      <designateRulesPursuantThisScheduleFiled>
        <designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
      </designateRulesPursuantThisScheduleFiled>
    </coverPageHeader>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Solas Tvardi Sidecar LLC</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>TN</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>598288.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>598288.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>761287.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>8.1</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Solas BioVentures Fund II, LP</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>162999.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>162999.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>761287.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>8.1</classPercent>
      <typeOfReportingPerson>PN</typeOfReportingPerson>
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    <coverPageHeaderReportingPersonDetails>

      <reportingPersonName>Solas Partners II, LLC</reportingPersonName>
      <memberGroup>b</memberGroup>
      <citizenshipOrOrganization>DE</citizenshipOrOrganization>
      <reportingPersonBeneficiallyOwnedNumberOfShares>
        <soleVotingPower>0.00</soleVotingPower>
        <sharedVotingPower>761287.00</sharedVotingPower>
        <soleDispositivePower>0.00</soleDispositivePower>
        <sharedDispositivePower>761287.00</sharedDispositivePower>
      </reportingPersonBeneficiallyOwnedNumberOfShares>
      <reportingPersonBeneficiallyOwnedAggregateNumberOfShares>761287.00</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
      <classPercent>8.1</classPercent>
      <typeOfReportingPerson>OO</typeOfReportingPerson>
    </coverPageHeaderReportingPersonDetails>
    <items>
      <item1>
        <issuerName>Tvardi Therapeutics, Inc.</issuerName>
        <issuerPrincipalExecutiveOfficeAddress>3 SUGAR CREEK CTR. BLVD., STE 525, SUGAR LAND, TEXAS, 77478</issuerPrincipalExecutiveOfficeAddress>
      </item1>
      <item2>
        <filingPersonName>Solas Tvardi Sidecar, LLC
Solas BioVentures Fund II, LP
Solas Partners II, LLC</filingPersonName>
        <principalBusinessOfficeOrResidenceAddress>All entities:

412 Georgia Ave., STE 201
Chattanooga, TN 37403</principalBusinessOfficeOrResidenceAddress>
        <citizenship>Solas Tvardi Sidecar, LLC:        Tennessee
Solas BioVentures Fund II, LP:  Delaware
Solas Partners II, LLC:              Delaware</citizenship>
      </item2>
      <item3>
        <notApplicableFlag>Y</notApplicableFlag>
      </item3>
      <item4>
        <amountBeneficiallyOwned>Please see Row 9 of each Reporting Person's cover page</amountBeneficiallyOwned>
        <classPercent>Please see Row 11 of each Reporting Person's cover page</classPercent>
        <numberOfSharesPersonHas>
          <solePowerOrDirectToVote>Please see Row 5 of each Reporting Person's cover page</solePowerOrDirectToVote>
          <sharedPowerOrDirectToVote>Please see Row 6 of each Reporting Person's cover page</sharedPowerOrDirectToVote>
          <solePowerOrDirectToDispose>Please see Row 7 of each Reporting Person's cover page</solePowerOrDirectToDispose>
          <sharedPowerOrDirectToDispose>Please see Row 8 of each Reporting Person's cover page</sharedPowerOrDirectToDispose>
        </numberOfSharesPersonHas>
      </item4>
      <item5>
        <notApplicableFlag>Y</notApplicableFlag>
        <classOwnership5PercentOrLess>N</classOwnership5PercentOrLess>
      </item5>
      <item6>
        <notApplicableFlag>Y</notApplicableFlag>
      </item6>
      <item7>
        <notApplicableFlag>Y</notApplicableFlag>
      </item7>
      <item8>
        <notApplicableFlag>N</notApplicableFlag>
        <identificationAndClassificationOfGroupMembers>Solas Tvardi Sidecar, LLC
Solas BioVentures Fund II, LP
Solas Partners II, LLC</identificationAndClassificationOfGroupMembers>
      </item8>
      <item9>
        <notApplicableFlag>Y</notApplicableFlag>
      </item9>
      <item10>
        <notApplicableFlag>N</notApplicableFlag>
        <certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.

</certifications>
      </item10>
    </items>
    <signatureInformation>
      <reportingPersonName>Solas Tvardi Sidecar LLC</reportingPersonName>
      <signatureDetails>
        <signature>Mark D Hackett</signature>
        <title>Manager of Solas Partners II, LLC, its Manager</title>
        <date>04/22/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Solas BioVentures Fund II, LP</reportingPersonName>
      <signatureDetails>
        <signature>Mark D Hackett</signature>
        <title>Manager of Solas Partners II, LLC, its General Partner</title>
        <date>04/22/2025</date>
      </signatureDetails>
    </signatureInformation>
    <signatureInformation>
      <reportingPersonName>Solas Partners II, LLC</reportingPersonName>
      <signatureDetails>
        <signature>Mark D Hackett</signature>
        <title>Manager</title>
        <date>04/22/2025</date>
      </signatureDetails>
    </signatureInformation>
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</SEC-DOCUMENT>
