<SEC-DOCUMENT>0001104659-25-014310-index.html : 20250214
<SEC-HEADER>0001104659-25-014310.hdr.sgml : 20250214
<ACCEPTANCE-DATETIME>20250214171351
ACCESSION NUMBER:		0001104659-25-014310
CONFORMED SUBMISSION TYPE:	424B3
PUBLIC DOCUMENT COUNT:		18
FILED AS OF DATE:		20250214
DATE AS OF CHANGE:		20250214

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Cara Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001346830
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		IRS NUMBER:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		424B3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-283900
		FILM NUMBER:		25630863

	BUSINESS ADDRESS:	
		STREET 1:		400 ATLANTIC STREET, SUITE 500
		CITY:			STAMFORD
		STATE:			CT
		ZIP:			06901
		BUSINESS PHONE:		203-406-3700

	MAIL ADDRESS:	
		STREET 1:		400 ATLANTIC STREET, SUITE 500
		CITY:			STAMFORD
		STATE:			CT
		ZIP:			06901

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cara Therapeutics Inc
		DATE OF NAME CHANGE:	20051213
</SEC-HEADER>
<DOCUMENT>
<TYPE>424B3
<SEQUENCE>1
<FILENAME>tm2430195-17_424b3.htm
<DESCRIPTION>424B3
<TEXT>
Document 1 - file: tm2430195-17_424b3.htm

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<SEQUENCE>2
<FILENAME>lg_caratmtherap-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 2 - file: lg_caratmtherap-4c.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>3
<FILENAME>fc_pipeline-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 3 - file: fc_pipeline-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>fc_canonical-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: fc_canonical-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>fc_dualmechanism-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: fc_dualmechanism-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>fc_centralcatalyst-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: fc_centralcatalyst-4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>fc_currentpipeline-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: fc_currentpipeline-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>8
<FILENAME>fc_ipfaffected-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 8 - file: fc_ipfaffected-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>fc_lungfibrosis-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: fc_lungfibrosis-4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>bc_bothextrinsic-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: bc_bothextrinsic-4clr.jpg

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<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>bc_dosedepen-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: bc_dosedepen-4clr.jpg

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<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>fc_evaluating-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: fc_evaluating-4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>13
<FILENAME>fc_mousemodel-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 13 - file: fc_mousemodel-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>14
<FILENAME>fc_engrafted-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 14 - file: fc_engrafted-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>15
<FILENAME>lc_treatment-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 15 - file: lc_treatment-4clr.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>16
<FILENAME>fc_clinicaltrial-4clr.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 16 - file: fc_clinicaltrial-4clr.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>px_25caraproxy1pg01-bw.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 17 - file: px_25caraproxy1pg01-bw.jpg

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<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>px_25caraproxy1pg02-bw.jpg
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<TEXT>
Document 18 - file: px_25caraproxy1pg02-bw.jpg

</DOCUMENT>
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