<SEC-DOCUMENT>0001104659-26-054113-index.html : 20260501
<SEC-HEADER>0001104659-26-054113.hdr.sgml : 20260501
<ACCEPTANCE-DATETIME>20260501160529
ACCESSION NUMBER:		0001104659-26-054113
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		21
FILED AS OF DATE:		20260501
DATE AS OF CHANGE:		20260501

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Tvardi Therapeutics, Inc.
		CENTRAL INDEX KEY:			0001346830
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-295496
		FILM NUMBER:		26932429

	BUSINESS ADDRESS:	
		STREET 1:		3 SUGAR CREEK CTR. BLVD.
		STREET 2:		STE 525
		CITY:			SUGAR LAND
		STATE:			TX
		ZIP:			77478
		BUSINESS PHONE:		(713) 489-8654

	MAIL ADDRESS:	
		STREET 1:		3 SUGAR CREEK CTR. BLVD.
		STREET 2:		STE 525
		CITY:			SUGAR LAND
		STATE:			TX
		ZIP:			77478

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cara Therapeutics, Inc.
		DATE OF NAME CHANGE:	20100721

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Cara Therapeutics Inc
		DATE OF NAME CHANGE:	20051213
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>tm2613101-1_s3.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: tm2613101-1_s3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.2
<SEQUENCE>2
<FILENAME>tm2613101d2_ex1-2.htm
<DESCRIPTION>EXHIBIT 1.2
<TEXT>
Document 2 - file: tm2613101d2_ex1-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.2
<SEQUENCE>3
<FILENAME>tm2613101d2_ex4-2.htm
<DESCRIPTION>EXHIBIT 4.2
<TEXT>
Document 3 - file: tm2613101d2_ex4-2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.4
<SEQUENCE>4
<FILENAME>tm2613101d2_ex4-4.htm
<DESCRIPTION>EXHIBIT 4.4
<TEXT>
Document 4 - file: tm2613101d2_ex4-4.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.5
<SEQUENCE>5
<FILENAME>tm2613101d2_ex4-5.htm
<DESCRIPTION>EXHIBIT 4.5
<TEXT>
Document 5 - file: tm2613101d2_ex4-5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.6
<SEQUENCE>6
<FILENAME>tm2613101d2_ex4-6.htm
<DESCRIPTION>EXHIBIT 4.6
<TEXT>
Document 6 - file: tm2613101d2_ex4-6.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>7
<FILENAME>tm2613101d2_ex5-1.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 7 - file: tm2613101d2_ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>8
<FILENAME>tm2613101d2_ex23-1.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 8 - file: tm2613101d2_ex23-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-FILING FEES
<SEQUENCE>9
<FILENAME>tm2613101d1_ex-filingfees.htm
<DESCRIPTION>EX-FILING FEES
<TEXT>
Document 9 - file: tm2613101d1_ex-filingfees.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>lg_tvardi-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: lg_tvardi-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>11
<FILENAME>tb_pipeline-4c.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 11 - file: tb_pipeline-4c.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>12
<FILENAME>tm2613101d2_ex5-1img01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 12 - file: tm2613101d2_ex5-1img01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>14
<FILENAME>R1.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 14 - file: R1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>15
<FILENAME>R2.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 15 - file: R2.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>16
<FILENAME>R3.htm
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 16 - file: R3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>17
<FILENAME>report.css
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 17 - file: report.css

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>18
<FILENAME>Show.js
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 18 - file: Show.js

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>20
<FILENAME>FilingSummary.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 20 - file: FilingSummary.html

Document 20 - RAW XML: FilingSummary.xml

</DOCUMENT>
<DOCUMENT>
<TYPE>JSON
<SEQUENCE>22
<FILENAME>MetaLinks.json
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 22 - file: MetaLinks.json

</DOCUMENT>
<DOCUMENT>
<TYPE>ZIP
<SEQUENCE>23
<FILENAME>0001104659-26-054113-xbrl.zip
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 23 - file: 0001104659-26-054113-xbrl.zip

</DOCUMENT>
<DOCUMENT>
<TYPE>XML
<SEQUENCE>24
<FILENAME>tm2613101d1_ex-filingfees_htm.xml
<DESCRIPTION>IDEA: XBRL DOCUMENT
<TEXT>
Document 24 - file: tm2613101d1_ex-filingfees_htm.html

Document 24 - RAW XML: tm2613101d1_ex-filingfees_htm.xml

</DOCUMENT>
</SEC-DOCUMENT>